Member:Jin-Chul Heo (KR)


Short Biography

I am PhD and worked after PhD in Artificial Intelligence and Computed Diagnosis Lab(AICD) at the Keimyung University, Daegu, South Korea. My work is in research on atopic dermatitis diagnosis and treatment using optics.


  • Chungnam National University, Daejeon, Korea
    • Ph.D. Graduate, Microbiology (2009)
    • Graduate Researcher: Characteristics of anti-asthmatic agents from chemical libraries and natural products for early drug discovery


Journal Articles

  1. Ji-Ae Park, Hee-Jeong Han, Jin-Chul Heo, and Jong-Ha Lee, "aided diagnosis sensor integrated outdoor shirts for real time heart disease monitoring," Computer Assisted Surgery, vol. 22, no. S1, pp. 176-185, Oct. 2017
  2. Heo JC, Jung TH, Lee S, Kim HY, Choi G, Jung M, Jung D, Lee HK, Lee JO, Park JH, Hwang D, Seol HJ, Cho H. Effect of bexarotene on differentiation ofglioblastoma multiforme compared with ATRA. Clin Exp Metastasis. 2016 Mar 8.[Epub ahead of print] PubMed PMID: 26957434.
  3. Elkamhawy A, Viswanath AN, Pae AN, Kim HY, Heo JC, Park WK, Lee CO, Yang H,Kim KH, Nam DH, Seol HJ, Cho H, Roh EJ. Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastomamultiforme (GBM). Eur J Med Chem. 2015 Oct 20;103:210-22. doi:10.1016/j.ejmech.2015.08.001. Epub 2015 Aug 4. PubMed PMID: 26355532.
  4. Park YB, Seo S, Kim JA, Heo JC, Lim YC, Ha CW. Effect of chondrocyte-derivedearly extracellular matrix on chondrogenesis of placenta-derived mesenchymal stemcells. Biomed Mater. 2015 Jun 24;10(3):035014. doi:10.1088/1748-6041/10/3/035014. PubMed PMID: 26107298.
  5. Choi SW, Yeon JT, Ryu BJ, Kim KJ, Moon SH, Lee H, Lee MS, Lee SY, Heo JC, Park SJ, Kim SH. Repositioning Potential of PAK4 to Osteoclastic Bone Resorption. J Bone Miner Res. 2015 Aug;30(8):1494-507. doi: 10.1002/jbmr.2468. Epub 2015 May21. PubMed PMID: 25640698.
  6. Shin YK, Son HU, Kim JM, Heo JC, Lee SH, Kim JG. Cinnamomum cassia bark produced by solid-state fermentation with Phellinus baumii has the potential to alleviate atopic dermatitis-related symptoms. Int J Mol Med. 2015 Jan;35(1):187-94. doi:10.3892/ijmm.2014.2006. Epub 2014 Nov 18. PubMed PMID:25406033.
  7. Yeon JT, Ryu BJ, Choi SW, Heo JC, Kim KJ, Son YJ, Kim SH. Natural polyamines inhibit the migration of preosteoclasts by attenuating Ca2+-PYK2-Src-NFATc1 signaling pathways. Amino Acids. 2014 Nov;46(11):2605-14. doi:10.1007/s00726-014-1797-9. Epub 2014 Sep 13. PubMed PMID: 25216923.
  8. Heo JC, Jung TH, Jung DY, Park WK, Cho H. Indatraline inhibits Rho- and calcium-mediated glioblastoma cell motility and angiogenesis. Biochem Biophys ResCommun. 2014 Jan 10;443(2):749-55. doi: 10.1016/j.bbrc.2013.12.046. Epub 2013 Dec12. PubMed PMID: 24333442.
  9. Heo JC, Lee SH. Alleviation of asthma-related symptoms by a derivative of L-allo threonine. Int J Mol Med. 2013 Apr;31(4):881-7. doi:10.3892/ijmm.2013.1265. Epub 2013 Feb 1. PubMed PMID: 23381610.
  10. Heo JC, Son HU, Kim SL, Lee SH. A derivative of L-allo threonine alleviates 2,4-dinitrofluorobenzene-induced atopic dermatitis indications. Biosci BiotechnolBiochem. 2012;76(11):2021-5. Epub 2012 Nov 7. PubMed PMID: 23132584.
  11. Nam DY, Lee JM, Heo JC, Lee SH. Mitigation of 2,4-dinitrofluorobenzene-induced atopic dermatitis-related symptoms by Terminalia chebula Retzius. Int J Mol Med. 2011 Dec;28(6):1013-8. doi:10.3892/ijmm.2011.792. Epub 2011 Sep 7. PubMed PMID: 21901245.
  12. Heo JC, Nam DY, Seo MS, Lee SH. Alleviation of atopic dermatitis-related symptoms by Perilla frutescens Britton. Int J Mol Med. 2011 Nov;28(5):733-7. doi:10.3892/ijmm.2011.763. Epub 2011 Aug 2. PubMed PMID: 21811759.
  13. Lee HJ, Park CH, Son HU, Heo JC, Nam SH, Lee KG, Yeo JH, Yoon CS, Kim JM,Shin YK, Kim SO, Lee SH. Reduction of matrix metalloproteinase-9 expression by culture filtrate of Paecilomyces farinosus J3. Exp Ther Med. 2011 Mar;2(2):357-362. Epub 2011 Jan 20. PubMed PMID: 22977510; PubMed Central PMCID: PMC3440676.
  14. Park CH, Nam DY, Son HU, Lee SR, Lee HJ, Heo JC, Cha TY, Baek JH, Lee SH. Polymer fraction of Aloe vera exhibits a protective activity on ethanol-induced,gastric lesions. Int J Mol Med. 2011 Apr;27(4):511-8. doi: 10.3892/ijmm.2011.609.Epub 2011 Feb 1. PubMed PMID: 21286662.
  15. Heo JC, Nam SH, Nam DY, Kim JG, Lee KG, Yeo JH, Yoon CS, Park CH, Lee SH.,Anti-asthmatic activities in mycelial extract and culture filtrate of Cordyceps,sphecocephala J201. Int J Mol Med. 2010 Sep;26(3):351-6. PubMed PMID: 20664950.
  16. Son M, Kim A, Lee J, Park CH, Heo JC, Lee HJ, Lee SH. Ethanol extract of,Lycoris radiata induces cell death in B16F10 melanoma via p38-mediated AP-1 activation. Oncol Rep. 2010 Aug;24(2):473-8. PubMed PMID: 20596635.
  17. Heo JC, Park CH, Lee HJ, Kim SO, Kim TH, Lee SH. Amelioration of asthmaticinflammation by an aqueous extract of Spinacia oleracea Linn. Int J Mol Med. 2010 Mar;25(3):409-14. PubMed PMID: 20127046.
  18. Heo JC, Rho JR, Kim TH, Kim SY, Lee SH. An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers. Int J Mol Med. 2008 Dec;22(6):763-7. PubMed PMID: 19020774.
  19. Heo JC, Son M, Woo SU, Kweon MA, Yoon EK, Lee HK, Choi WS, Cho KJ, Lee SH. A fraction of methylene chloride from Geum japonicum Thunberg inhibits tumormetastatic and angiogenic potential. Oncol Rep. 2008 Jun;19(6):1399-403. PubMed PMID: 18497943.
  20. Heo JC, Woo SU, Kweon MA, Park JY, Lee HK, Son M, Rho JR, Lee SH. Aqueous extract of the Helianthus annuus seed alleviates asthmatic symptoms in vivo. Int J Mol Med. 2008 Jan;21(1):57-61. PubMed PMID: 18097616.
  21. Heo JC, Woo SU, Son M, Park JY, Choi WS, Chang KT, Kim SU, Yoon EK, Kim YH, Shin HM, Lee SH. Anti-tumor activity of Gastrodia elata Blume is closely associated with a GTP-Ras-dependent pathway. Oncol Rep. 2007 Oct;18(4):849-53.PubMed PMID: 17786345.
  22. An SM, Park CH, Heo JC, Park JY, Woo SU, Seo JH, Lee MS, Cho KJ, Cho HS, Shin HM, Lee SH. Gastrodia elata Blume protects against stress-induced gastric mucosal lesions in mice. Int J Mol Med. 2007 Aug;20(2):209-15. PubMed PMID: 17611639.
  23. Heo JC, Lee SH. Isolation and molecular taxonomy of two predominant types of microflora in Kefir. J Gen Appl Microbiol. 2006 Dec;52(6):375-9. PubMed PMID: 17325451.
  24. Heo JC, Park JY, Woo SU, Rho JR, Lee HJ, Kim SU, Kho YH, Lee SH. Dykellic acid inhibits cell migration and tube formation by RhoA-GTP expression. Biol Pharm Bull. 2006 Nov;29(11):2256-9. PubMed PMID: 17077524.
  25. Heo JC, Park JY, Lee JM, Kwon TK, Kim SU, Chung SK, Lee SH. Wisteria floribunda gall extract inhibits cell migration in mouse B16F1 melanoma cells by regulating CD44 expression and GTP-RhoA activity. J Ethnopharmacol. 2005 Oct 31;102(1):10-4. PubMed PMID: 16023319.
  26. Moon SH, Heo JC, Fine RL, Kim HM, Kim SU, Yoon BD, Lee SH. BRD-glucan exhibits potent immunochemotherapeutic activity in vitro and in vivo. Int J Oncol. 2005 Feb;26(2):395-404. PubMed PMID: 15645124.
  27. Song H, Kim SI, Ko MS, Kim HJ, Heo JC, Lee HJ, Lee HS, Han IS, Kwack K, Park JW. Overexpression of DRG2 increases G2/M phase cells and decreases sensitivity to nocodazole-induced apoptosis. J Biochem. 2004 Mar;135(3):331-5. PubMed PMID: 15113831.
  28. Chae SC, Song JH, Heo JC, Lee YC, Kim JW, Chung HT. Molecular variations in the promoter and coding regions of human Tim-1 gene and their association in Koreans with asthma. Hum Immunol. 2003 Dec;64(12):1177-82. PubMed PMID: 14630400.

International Conferences

  1. J-Chul Heo, Yoon Nyun Kim, Ji Ae Park, Chan-Il Kim, Su Yang, Jong-Ha Lee, "The Relative Impact of Tissue Effects on Implanted ECG Sensor Operation", The 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society , Aug. 2016.

Domestic Conferences


  1. 아미노산계 유도체를 포함하는 호흡기 질환의 예방, 개선 또는 치료하기 위한 의약 및 기능성 식품 조성물 10-1076769-0000 (대한민국)
  2. 바실러스속 미생물을 함유하는 쌀겨발효용 조성물 10-1057504-0000 (대한민국)
  3. 포도 추출물을 유효성분으로 함유하는 항암용 조성물 10-0913437-0000 (대한민국)
  4. 포도 추출물을 유효성분으로 함유하는 천식, 아토피 또는 비염의 예방 또는 치료용 조성물 10-0913436-0000 (대한민국)
  5. 2-메틸-2'-하이드록시메틸-6-아미도 벤조피란 유도체 또는 약제학적으로 허용 가능한 그의 염 및 그를 유효성분으로 함유하는 치매 및 뇌졸중 치료를 위한 약학적 조성물 10-0907475-0000 (대한민국)
  6. 항천식 활성을 가지는 신선초 추출물 10-0825869-0000 (대한민국)
  7. 항천식 활성을 가지는 해바라기 씨 추출물 10-0743959-0000 (대한민국)
  8. 항염증 활성을 갖는 무당벌레 추출물 및 이를 함유하는 조성물 10-0665000-0000 (대한민국)
  9. 다이켈릭산 또는 그 염을 유효성분으로 함유하는 암전이억제용 의약조성물 10-0605319-0000 (대한민국)
  10. 알코올 분해 촉진능을 가지는 물질의 초고속 스크리닝방법 10-0603494-0000 (대한민국)
  11. 암세포의 증식억제 활성을 가지는 등나무 추출물 및 이를함유하는 조성물 10-0603495-0000 (대한민국)

Honors and Awards

Contact Information

  • Postal (Visiting) Address: Department of Biomedical Engineering, M216, College of Medicine ,Keimyung University, South Korea
  • 주소: 대구광역시 달서구 신당동 계명대학교 의과대학 M216
  • Phone: (+82) 53 - 580 - 3807
  • Fax: (+82) 53 - 580 - 3730
  • Email: